Our research activities are within medicinal chemistry, drug discovery. Our main focus is on G protein-coupled receptors (GPCRs) and we have especially interested in the free fatty acid receptors, a group of receptors that has great potential as drug targets.
The FFARMED project is an international project that focus on exploring the activity of food constituents on free fatty acid receptors and take advantage of these to counteract type 2 diabetes.
We are also interested in various other targets within inflammation and metabolic diseases, including chemokine receptors and the energy level monitoring kinase AMPK.
Our medicinal chemistry projects revolved design – synthesis – evaluation to map structure-activity relationships and efficiently identify compounds with desired properties. Much of our effort go into synthesis and we continuously aim at developing simpler and more efficient, as well as greener, synthetic methods that can be useful to medicinal chemistry.